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国立成育医療研究センターについて About National Center for Child Health and Development

国立成育医療研究センターについて About National Center for Child Health and Development

The Japan Drug Information Institute in Pregnancy

Effects of Medications During Breast Feeding

  • This is a table for the effects of medication during breastfeeding (It is not a table for the effects of medication during pregnancy).
  • The table “Medications Considered Safe for Use” is evaluated based on current scientific knowledge of these drugs, and are currently believed to be safe to use during the nursing period.
  • The table “Medications Unfit for Use during Breastfeeding” is evaluated based on the comparison between the illness and its medication, and was concluded that the medication clearly should not be used during breastfeeding.
  • Medications not listed on these tables does not mean they are unfit for use or considered safe for use during breastfeeding.
  • Anticancer drugs were not listed in the table because the nature of the condition as well as information on these drugs are limited, making it difficult to evaluate the drug briefly without causing misinterpretations. Immunosuppressive drugs are not on the list as well.
  • It is essential to consult with your doctor about your medication. Don’t decide to continue or discontinue the use of medication by yourself.

Medications Considered Safe for Use

Generic Name Representative Brand* Primary Uses
Acyclovir Zovirax Antiviral medicine
Azithromycin Zithromax Antibiotic
Aztreonam Azactam Antibiotic
Acetazolamide Diamox Diuretic
Acetoaminophen Calonal Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
Amlodipine Norvasc Antihypertensive Drug
Amoxicillin Sawacillin/Pasetosin Antibiotic
Albendazole Eskazole Antiparasitic Drug
Allopurinol Zyloric Gout Suppressant agent
Ampicillin Viccillin Antibiotic
Ampicillin/>Cloxacillin Viccillin S Antibiotic
Isoniazid Iscotin Antibiotic
ibuprofen Brufen Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
Ivermectin Stromectol Antiparasitic Drug
Imipenem/-cilastatin Tienam Antibiotic
Insulin Diabetes Treatment
Indomethacin Inteban (Indocin) Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
infliximab Remicade Antirheumatic Drug
Ursodeoxycholic Acid (Ursodiol) Urso Digestive System Treatment
Etanercept Enbrel Antirheumatic Drug
Ethanbutol Ethanbutol(Myambutol) Antibiotic
Enalapril Renivace (Epaned) Antihypertensive Drug
Erythromycin Erythrocin Antibiotic
Eletriptan Relpax Migraine medication
Oseltamivir Tamiflu Antiviral medicine
Ofloxacin Tarivid (Floxin, Ocuflox) Antibiotic
Captopril Captopril (Capoten) Antihypertensive Drug
Calcitriol Rocaltrol Vitamin D medication
Quinidine Quinidine Sulfate (Quinidex) Antiarrhythmic drug
Clarithromycin Clarith (Biaxin) Antibiotic
Clindamycin Dalacin (Cleocin) Antibiotic
Cloxacillin Viccillin S Antibiotic
Ketoprofen Capisten (Orudis, Oruvail) Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
ciprofloxacin Ciproxan (Cipro) Antibiotic
Cimetidine Tagamet Digestive System Treatment
Diclofenac Voltaren (Cambia, Cataflam) Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
Digoxin Digosin (Lanoxin) Cardiotonic medicine/ Heart Treatment
Diphenhydramine Vena (Allermax, Benadryl, etc) Antihistamine medicine
Dimenhydrinate Dramamine Antivertigo drug
Diltiazem Herbesser (Cardizem) Antihypertensive Drug
Spironolactone Aldactone Diuretic
Sumatriptan Imigran (Sumavel Dose Pro) Migraine Medication
Cefaclor Kefral (Raniclor) Antibiotic
Cefazolin Cefamezin Antibiotic
Cefadroxil Dolucephan (Duricef) Antibiotic
Cephalexin Keflex (Panixine) Antibiotic
Cefotaxime Cefotax (Claforan) Antibiotic
Cefoperazone Cefoperazin (Cefobid) Antibiotic
Ceftazidime Modacin (Mortaf, Tazicef) Antibiotic
Ceftizoxime Eposerin (Cefizox) Antibiotic
Ceftraxone Rocephin Antibiotic
Cefuroxime Oracef (Zinacef) Antibiotic
Senna, Senocide Alosenn, pursennid Digestive System Treatment
Somatropin Genotropin Growth Hormone
Dalteparin Fragmin Antithrombotic drug
Theophylline Theodore (Quibron-T) Asthmatic Medicine
Tetracycline Achromycin (Ala-Tet, Panmycin) Antibiotic
Turbutaline Bricanyl Asthmatic Medicine
Desmopressin Desmopressin (DDAVP) Hormone
Triprolidine Venen (Vanahist PD) Antihistamine medicine
Doxycycline Vibramycin (Acticlate, Adoxa, etc) Antibiotic
Domperidone Nauzelin Digestive System Treatment
Naproxen Naixan (Aleve, Anaprox, etc) Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
Nicardipine Perdipine (Cardene IV) Antihypertensive Drug
Nizatidine Acinon (Axid) Digestive System Treatment
Nifedipine Adalert (Adalat, CC, Afeditab CR, etc) Antihypertensive Drug
Norfloxacin Baccidal (Noroxin) Antibiotic
Valaciclovir Valtrex Antiviral medicine
Vancomycin Vancomycin Antibiotic
Hydralazine Apresoline Antihypertensive Drug
Piperacillin Pentcillin Antibiotic
Pyrazinamide Pyramide Antibiotic
Piroxicam Baxo (Feldene) Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
Famotidine Gaster (Heartburn Relief, Pepcid, etc) Digestive System Treatment
Filgrastim Gran (Neupogen) Hormone
Fexofenadine Allegra Antihistamine
Fluconazole Diflucan Antifungal drug
Flurbiprofen Froben Antipyretic and analgesic drug/ Fever reducer and Pain Reliever
Flecainide Tambocor Antiarrhythmic drug
Budesonide Pulmicort (Entocort EC, Uceris) Inhaled Steroids
Procainamide Amisalin Antiarrhythmic drug
Verapamil Vasolan (Calan, Verelan, etc) Antiarrhythmic drug
Benzylpenicillin Penicillin G Antibiotic
Fosfomycin Fosmicin (Monurol) Antibiotic
Mexiletine Mexitil Antiarrhythmic drug
Methyldopa Aldomet Antihypertensive Drug
Moxifloxacin Avelox Antibiotic
Ranitidine Zantac (Taladine) Digestive System Treatment
Labetalol Trandate Antihypertensive Drug
Triiodothyronine Thyronamine Thyroid Hormone
Lidocaine Xylocaine (Zingo) Antiarrhythmic drug and anesthetic
Rifampicin Rifadin IV Antibiotic
Levothyroxine Thyradin S (Levothroid, Levoxyl) Thyroid Hormone
Levofloxacin Cravit (Levaquin) Antibiotic
Loperamide Lopemin (Diamode, Imodium) Digestive System Treatment
Loratadine Claritin (Alavert) Antihistamine
Warfarin Warfarin (Coumadin, Jantoven) Antithrombotic drug
Quinine Hydrochloride Quinine Hydrochloride (Qualaquin, QM-260) Antimalarial drug
Magnesium Sulfate Magnesium Sulfate (Epsom Salt) Digestive System Treatment

Medications Unfit for Use during Breastfeeding

Generic Name Representative Brand* Primary Uses
Amiodarone Ancaron (Cordarone, Pacerone) Antiarrhythmic Drug
Cocaine Cocaine Narcotic
Sodium Iodide (I-123) Iodine Capsule-123 Radioiodine
Sodium Iodide (I-131) Sodium Iodide (131I) Capsules Radioiodine

*The brand names in brackets () are names used in countries outside of Japan.